FIG. 1.
Effects of SSG-NIV treatment on the parasite burdens in the spleens livers and bone marrows of mice infected with different L. donovani strains. BALB/c mice were infected with different strains of L. donovani amastigotes and treated on day 7 with PBS (controls) or different doses of SSG-NIV. On day 14 postinfection, parasite burdens in the spleen (A), liver (B), and bone marrow (C) were determined. The mean reduction in parasite burdens was calculated using the mean control burdens for the relevant site.