Table 3.

Odds ratios for main effects and interactions between sex, substance use diagnosis, and new vs. absent PTSD diagnoses.

	Main effects
	New vs. Absent PTSD dx (REF Absent PTSD dx)
	Odds Ratio	95% CI	p-value
Substance use disorder
Female	2.03	1.20–3.44	0.01
New SUD dx	3.14	1.58–5.26	<0.01
Remit SUD dx	3.51	1.75–7.05	<0.01
Ongoing SUD dx	5.28	2.81–9.92	<0.01
Sex-specific analyses
Males
New SUD dx	2.11	0.64–6.99	0.22
Remit SUD dx	3.59	1.16–11.13	0.03
Ongoing SUD dx	4.98	1.88–13.22	<0.01
Females
New SUD dx	3.98	1.66–9.55	<0.01
Remit SUD dx	3.37	1.55–7.30	<0.01
Ongoing SUD dx	5.39	2.53–11.51	<0.01
Alcohol use disorder
Female	1.94	1.23–3.34	0.02
New AUD dx	2.53	1.17–5.47	0.02
Remit AUD dx	3.94	1.94–8.00	<0.01
Ongoing AUD dx	3.67	1.88–7.19	<0.01
Sex-specific analyses
Males
New AUD dx	2.08	0.72–5.97	0.17
Remit AUD dx	4.08	1.33–12.49	0.16
Ongoing AUD dx	2.11	0.75–5.96	0.05
Females
New AUD dx	2.86	1.00–8.17	0.05
Remit AUD dx	3.59	1.66–7.78	<0.01
Ongoing AUD dx	5.33	2.43–11.68	<0.01
Drug use disorder
Female	1.93	1.15–3.25	0.01
New DUD dx	8.11	3.51–18.74	<0.01
Remit DUD dx	3.78	1.85–7.61	<0.01
Ongoing DUD dx	6.24	3.17–12.29	<0.01
Sex-specific analyses
Males
New DUD dx	10.32	3.12–34.18	<0.01
Remit DUD dx	4.49	1.72–11.74	<0.01
Ongoing DUD dx	2.37	0.55–10.21	0.25
Females
New DUD dx	5.54	2.21–13.86	<0.01
Remit DUD dx	3.06	1.12–8.37	0.03
Ongoing DUD dx	10.96	5.10–23.58	<0.01

SUD: substance use disorder; AUD: alcohol use disorder; DUD: drug use disorder; Dx: diagnosis; CI: confidence Interval.