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. 2022 May 9;79(6):584–591. doi: 10.1001/jamaneurol.2022.0976

Table 3. Unadjusted and Combined Population-Attributable Risk for 8 Modifiable Dementia Risk Factors Overall in the US, 2018.

Risk factor Relative risk (95% CI) Uniqueness, % Population-attributable risk, % (95% CI)
Hearing loss 1.4 (1.1-1.7)13 86.7 2.3 (2.2-2.3)
Current smoking 1.4 (1.2-1.6)14 46.9 6.0 (5.9-6.1)
Midlife hypertensiona 1.3 (1.1-1.4)14 22.1 8.8 (8.7-8.9)
Diabetes 1.7 (1.5-1.9)14 43.2 7.3 (7.1-7.4)
Depression 1.5 (1.1-2.0)14 74.1 8.5 (8.4-8.6)
Low education 2.0 (1.6-2.6)14 70.8 11.7 (11.5-12.0)
Physical inactivity 1.6 (1.3-1.8)14 67.5 11.8 (11.7-11.9)
Midlife obesity 1.6 (1.1-2.3)14 66.2 17.7 (17.5-18.0)
Combined NA NA 36.9 (36.5-37.3)
a

Midlife hypertension data were collected in 2017 because information on hypertension was not recorded in the 2018 survey.