Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Solanum nigrum extracts ameliorating apoptotic cascade of cancer/tumor cells by Flavonoids; Bax, Bak, and Bid are regulators of apoptosis. BcL-x, Bad, and BcL-2 are regulatory proteins for apoptosis cascade (inhibited by flavonoids), procaspase-9 and Apaf1 and cytochrome C combine to form apoptosome. Simultaneously, death receptors integrate with procaspase-8, triggering caspase-3 and activating apoptosis. 53
