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. 2018 Oct 15;8(61):35246–35256. doi: 10.1039/c8ra06665e

Specific endocytosis inhibitors indicating the affected mechanism.

Inhibitor Affected mechanism Target
Chlorpromazine Clathrin-dependent endocytosis Alteration of clathrin-coat assembly, membrane fluidity and permeability
Methyl-β-cyclodextrin Clathrin-independent endocytosis Caveolae and lipid raft internalizations
Cytochalasin D Macropinocytosis Blockage polymerization of actins avoiding microfilaments action and inhibition of other endocytosis routes
Nocodazole Macropinocytosis Inhibition of microtubule function involved in intracellular vesicle trafficking
Wortmannin Phagocytosis PI3K (selective) and other kinases as myosin light chain kinase and PI4K
Genistein Clathrin-independent endocytosis Inhibition of Src tyrosine kinases and caveolae dynamic