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. 2022 Apr 28;52(7):1120–1128. doi: 10.1002/eji.202249824

Figure 2.

Figure 2

Anti‐IFN‐I NAB were associated with laboratory biomarkers predictive for COVID‐19 outcome. Biochemical and hematological parameters levels in SARS‐CoV‐2‐infected patients, stratified by autoantibody status as anti‐IFN‐I BAB negative patients (total n = 299), anti‐IFN‐I BAB positive patients without NAB to IFN‐α subtypes, IFN‐β, and IFN‐ω (total n = 48), and anti‐IFN‐I NAB positive patients (total n = 13). CRP, C‐reactive protein (Panel A); LDH, lactate dehydrogenase (Panel B); d‐Dimer (Panel C); WBC, white blood cells (Panel D); neutrophils (Panel E); platelets (Panel F); NLR, neutrophils to lymphocytes ratio (Panel G); PLR, platelets to lymphocytes ratio (Panel H); lymphocytes (Panel I); monocytes (Panel L). Median values of biochemical and hematological parameters are reported, for each group of study, with a red horizontal line. Female patients are represented with open circle symbols while male patients with close circle symbols. *p < 0.05; **p < 0.01; ***p ≤ 0.001. Values of biochemical and hematological parameters were compared by Mann–Whitney test.