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. 2022 Mar 25;52(5):816–824. doi: 10.1002/eji.202149785

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© 2022 The Authors. European Journal of Immunology published by Wiley‐VCH GmbH.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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IgG concentrations and geometric mean concentrations (GMC) expressed as BAU/mL for WT spike proteins (SFL and RBD) in sera of elderly (n = 9) and health care workers (HCW) 21–42 (n = 8) or 43–77 (n = 12) days after booster mRNA vaccination (third dose) using Comirnaty or 21–42 (n = 1) and 43–77 (n = 4) days after using Spikevax. Each sample was tested as a technical duplicate in each experiment and the average of the two duplicates is shown. The experimental precision was confirmed by two positive control samples in each independent experiment.