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. 2022 Mar 25;52(5):816–824. doi: 10.1002/eji.202149785

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© 2022 The Authors. European Journal of Immunology published by Wiley‐VCH GmbH.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Neutralizing antibody (NAb) titers to WT virus and three variants of concern Delta (B.1.617.2), Beta (B.1.351), and Omicron (B.1.1.529) in elderly (n = 7) and health care workers (HCW) 21–42 (n = 8) or 43–77 (n = 12) daysafter third booster mRNA vaccination with Comirnaty or Spikevax COVID‐19 vaccine. Each sample was tested as a technical duplicate in each experiment and 50% inhibition of SARS‐CoV‐2 infection observed by the cytopathic effect of inoculated cells is shown. The experimental precision was confirmed by two positive control samples in each independent experiment.