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. 2021 Nov 13;156(3):406–417. doi: 10.1002/ijgo.14008

TABLE 1.

Study characteristics

Author Country Study design Vaccine type No. of doses administered before analysis N Population type
Esteve‐Paula et al. 23 Spain Observational cohort Pfizer Two 18 Lactating, vaccinated
Bertrand et al. 32 USA Observational cohort

Moderna (n = 52)

Pfizer (n = 128)

Moderna took both doses (n = 52)

Not clear for Pfizer

180 Lactating, vaccinated
Low et al. 28 Singapore Observational cohort Pfizer Two 25

Lactating, vaccinated (n = 10)

Lactating, infected, unvaccinated (n = 6)

Lactating, unvaccinated (n = 9)

Theiler et al. 37 USA Case‐control

Johnson (n = 1)

Modern (n = 12)

Pfizer (n = 127)

One (n = 37)

Two (n = 103)

2002

Pregnant, unvaccinated (n = 1862)

Pregnant, vaccinated (n = 140)

Selma‐Royo et al. 29 Spain Observational cohort

Pfizer (n = 30)

Moderna (n = 21)

AZ (n = 24)

Two for Pfizer and Moderna (n = 51), one for AZ (n = 24) 75

Lactating, vaccinated (n=75)

Lactating, infected, unvaccinated (n=19)

Lactating, pre‐pandemic (n=13)

Collier et al. 16 USA Observational cohort

Pfizer and Moderna

(pregnant: Pfizer = 11, Moderna = 19; lactating: Pfizer = 11, Moderna = 5; non‐pregnant: Pfizer = 34, Moderna = 23)

Not reported 131

Non‐pregnant, nonlactating, vaccinated (n = 57)

Pregnant, vaccinated (n = 30)

Lactating, vaccinated (n = 16)

Non‐pregnant, unvaccinated, infected (n = 6)

Pregnant, unvaccinated, infected (n = 22)

Beharier et al. 17 Israel Case‐control Pfizer One and two, numbers not specified 213

Pregnant, vaccinated (n = 86)

Pregnant, unvaccinated, infected (n = 65)

Pregnant, unvaccinated, non‐infected (n = 62)

Gray et al. 18 USA Observational cohort Pfizer and Moderna (pregnant: Pfizer = 41, Moderna = 43; lactating: Pfizer = 16, Moderna = 15; non‐pregnant: Pfizer = 8, Moderna = 8)

One (n = 6)

Two (n = 125)

131

Non‐pregnant, vaccinated (n = 16)

Pregnant, vaccinated (n = 84)

Lactating, vaccinated (n = 31)

Infected, unvaccinated (n = 37)

Mithal et al. 19 USA Observational cohort

Pfizer (n = 18)

Moderna (n = 6)

Unknown (n = 4)

One (n = 5)

Two (n = 22)

27 Pregnant, vaccinated
Perl et al. 30 Israel Observational cohort Pfizer Two 84 Lactating, vaccinated
Friedman et al. 24 Israel Observational cohort Pfizer Two 10 Lactating, vaccinated
Golan et al. 25 USA Observational cohort

Moderna (n = 9)

Pfizer (n = 14)

Two 23

Lactating, vaccinated (n = 23)

Lactating, infected (n = 3)

Prabhu et al. 20 USA Observational cohort

Pfizer (n = 85)

Moderna (n = 37)

One (n = 55)

Two (n = 67)

122 Pregnant, vaccinated
Rottenstreich et al. 21 Israel Observational cohort Pfizer Two 20 Pregnant, vaccinated
Shanes et al. 39 USA Case‐control Not reported Not reported 200

Pregnant, vaccinated (n = 84)

Pregnant, unvaccinated (n = 116)

Atyeo et al. 22 USA Observational cohort

Pfizer (n = 65)

Moderna (n = 66)

Two 131

Pregnant, vaccinated (n = 84)

Lactating, vaccinated (n = 31)

Non‐pregnant, vaccinated (n = 16)

Fox et al. 31 USA Observational cohort

Pfizer (n = 6)

Moderna (n = 4)

Two 10 Lactating, vaccinated
Valcarce et al. 26 USA Observational cohort

Pfizer (n = 14)

Moderna (n = 7)

Two 21 Lactating, vaccinated
Shimabukuro et al. 33 USA Observational cohort

Pfizer (n = 19 252)

Moderna (n = 16 439)

One (n = 16 982)

Two (n = 12 273)

35 691 Pregnant, vaccinated
Juncker et al. 27 Netherlands Observational cohort Pfizer

One (n = 6)

Two (n = 20)

26 Lactating, vaccinated
Kadali et al. 34 USA Cross‐sectional

Pfizer (n = 20)

Moderna (n = 18)

One (n = 7)

Two (n = 31)

38 Pregnant, vaccinated
Low et al. 35 Singapore Observational cohort Pfizer Two 88 Lactating, vaccinated
McLaurin‐Jiang 36 USA Cross‐sectional

Pfizer (n = 2702)

Moderna (n = 1714)

One (n = 2627)

Two (n = 1828)

4455 Lactating, vaccinated