TABLE 6.
Laboratory tests in healthy pregnant women and pregnant women with three severity stages of COVID‐19 disease
| Healthy (n = 24) | Mild (n = 33) | Moderate (n = 10) | Severe (n = 10) | P value | |
|---|---|---|---|---|---|
| Leukocytes per mm3 | 9255 (4120–19 290)a,c | 6300 (4010–12 160)a | 6605 (3600–11 600)c | 8230 (4160–15 800) | 0.016 |
| Lymphocytes per mm3 | 1525 (213–3410)d,i | 1350 (600–2530)m,p | 855 (370–1200)d,m,t | 568.5 (112–1120)i,p,t | 0.001 |
| Neutrophils per mm3 | 6495 (2440–16 920)b,e,j | 4790 (2700–9640)b | 5080.5 (270–9500)e | 4196 (1420–9266)j | 0.043 |
| Platelets 103 per µl | 247.5 (35–386)f | 227 (146–346)n | 182.5 (149–452)f,n | 221 (132–645) | 0.161 |
| NLR | 3.95 (1.5–22.5) | 3.4 (1.5–14.7)q | 5.27 (0.3–10.9) | 6.85 (1.3–56.6)q | 0.169 |
| PLR | 166.25 (23.6–638.5)g,k | 195.6 (79.8–465)r | 226.93 (148.6–567.6)g | 539.7 (141.1–2053.6)k,r | 0.001 |
| Fibrinogen (mg/dl) | 656 (459–930) | 659.5 (340–877) | 598.5 (192–822)u | 783.5 (475–921)u | 0.200 |
| D‐dimer (ng/ml) | 450 (74–949)h,l | 411.5 (197–831)o,s | 705 (367–1935)h,o | 973 (404–1402)l,s | 0.001 |
Abbreviations: NLR, neutrophil/lymphocyte ratio; PLR, platelet/lymphocyte ratio.
Values are given as median (minimum and maximum).
Kruskal‐Wallis analysis.
Comparisons between each group Mann‐Whitney U test.
Healthy vs mild: a P < 0.004, b P < 0.013.
Healthy vs moderate: c P < 0.021, d P < 0.001, e P < 0.049, f P < 0.047, g P < 0.034, h P < 0.045.
Healthy vs severe: i P < 0.001, j P < 0.054, k P < 0.001, l P < 0.001.
Mild vs moderate: m P < 0.006, n P < 0.021, o P < 0.011.
Mild vs severe: p P < 0.001, q P < 0.041, r P < 0.001, s P < 0.001.
Moderate vs severe: t P < 0.034, u P < 0.041.