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. 2022 Apr 26;9:843234. doi: 10.3389/fmolb.2022.843234

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Copyright © 2022 Zhanghuang, Yao, Tang, Zhang, Wu, Li, Xie, Yang and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional enrichment analysis. (A) Volcano plot showing the DEGs of the risk score (high vs. low). Green: downregulated (Down), red: upregulated (Up), black: unchanged (no). (B) Heatmap based on 61 DEGs that were differentially expressed between high- and low-risk score samples. Each column represents a sample, and each row represents the mRNA level. Red indicates that the gene is upregulated, and green indicates downregulated genes. (C) Top 10 Gene Ontology terms enriched by the DEGs. (D) KEGG enrichment analysis of DEGs. The left side of the circle is the gene, and the right side is the pathway. Different colors represent different pathways, and the color of each pathway is annotated in right of the circle. If the gene belongs to a pathway, there will be a line between the gene and the pathway.