Table 4.
Summary of cases with high clinical suspicion for COVID‐19 but negative RT‐PCR for SARS‐CoV‐2 (n=8). a
| Variables | Values |
|---|---|
| Maternal age (years) | 32.62 ± 2.56 (21–40) |
| Gravidity | 2 (2.5, 1–7) |
| Parity | 1 (2.5, 0–4) |
| Living child | 1 (1.75, 0–4) |
| Previous miscarriage | 0 (0.75, 0–2) |
| Pre‐pregnancy BMI (kg/m2) | 25.30 ± 2.85 (19–28) |
| Route of admission to the hospital | |
| Emergency service | 3 (37.5) |
| Ambulance | 3 (37.5) |
| Referral from another hospital | 2 (25) |
| Co‐morbid disease | 4 (50) |
| ITP | 1 (25) |
| CHF | 1 (25) |
| CKD | 1 (25) |
| HT | 1 (25) |
| Gestational age at diagnosis (weeks) | 28.4 ± 17.8 (5–40) |
| Pregnancy trimester at diagnosis | |
| First | 1 (12.5) |
| Second | 1 (12.5) |
| Third | 3 (37.5) |
| Postpartum period | 3 (37.5) |
| Initial symptoms | |
| Fever | 5 (62.5) |
| Cough | 4 (50) |
| Dyspnea | 5 (62.5) |
| Myalgia | 2 (25) |
| Anosmia | 1 (12.5) |
| Close contact with a confirmed or suspected case | 3 (37.5) |
| Abnormal vital signs at admission to hospital | |
| Fever (body temperature ≥38 °C) | 5 (62.5) |
| Tachypnea (respiratory rate ≥20/min) | 1 (12.5) |
| Tachycardia (heart rate ≥100/min) | 1 (12.5) |
| Oxygen saturation ≤93% | 4 (50) |
| COVID‐19 therapy | 7 (87.5) |
| Hydroxychloroquine | 7 (87.5) |
| Azithromycin | 6 (75) |
| Oseltamivir | 4 (50) |
| Low molecular weight heparin | 4 (50) |
| Respiratory support | 4 (50) |
| Admission to ICU | 0 (0) |
| Length of hospital stay (days) | 4.37 ± 1.5 (3–7) |
| Nasal oxygen therapy | 4 (50) |
| Neutrophilia (>7700/mm3 or >70% of leukocytes) | 6 (75) |
| Lymphocytopenia (<1000/mm3 or <8% of leukocytes) | 4 (50) |
| Radiologic imaging | 7 (87.5) |
| Radiologic imaging findings suspicious for COVID‐19 | 7 (87.5) |
| Blood group | |
| A+ | 3 (37.5) |
| A‐ | 0 (0) |
| B+ | 1 (12.5) |
| B‐ | 0 (0) |
| AB+ | 2 (25) |
| AB‐ | 0 (0) |
| 0+ | 2 (25) |
| 0‐ | 0 (0) |
| Patients with pregnancy complications | 6 (75) |
| Pregnancy complication types | |
| Fetal growth restriction | 3 (37.5) |
| Preterm delivery | 3 (37.5) |
| Intrauterine fetal demise | 1 (12.5) |
| Oligohydramnios | 1 (12.5) |
| Pre‐eclampsia | 1 (12.5) |
| Preterm premature rupture of membranes | 1 (12.5) |
| Delivery status | |
| Ongoing pregnancy | 2 (25) |
| Delivered | 6 (75) |
| Route of delivery | |
| Normal spontaneous vaginal delivery | 3 (50) |
| Cesarean section | 3 (50) |
| Cesarean indications | |
| Fetal distress | 3 (100) |
| Labor anesthesia | |
| None | 3 (50) |
| General | 2 (33.3) |
| Regional | 1 (16.6) |
| Spontaneous labor | 2 (33.3) |
| Gestational age at delivery (weeks) | 34.2 ± 4.55 (28–40) |
| Birth weight (g) | 2350 ± 993.73 (1400–3700) |
| Apgar 1st minute | 6 (4, 3–9) |
| Apgar 5th minute | 8 (3.5, 5–10) |
| Admission to NICU | 3 (37.5) |
| Neonatal SARS‐CoV‐2 positivity | 0 (0) |
| Breastmilk positive for SARS‐CoV‐2 | 0 (0) |
Abbreviations: BMI, body mass index; CHF, chronic heart failure; CKD, chronic kidney disease; COVID‐19, coronavirus disease 2019; HT, hypertension; ICU, intensive care unit; ITP, immune thrombocytopenic purpura; NICU, neonatal intensive care unit; RT‐PCR, real‐time polymerase chain reaction; SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2.
a
Values are given as number (percentage), mean ± standard deviation (range), or median (interquartile range, range).