TABLE 1.
Characteristics of patients admitted to hospital for acute coronary syndrome (ACS) in each period compared with the reference pre-COVID-19 period.
| First wave period (24/02 to 27/04) |
Between waves period (28/04 to 20/09) |
Second wave period (21/09 to 27/12) |
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| Pre-COVID-19 | COVID-19 | % change | P-value | Pre-COVID-19 | COVID-19 | % change | P-value | Pre-COVID-19 | COVID-19 | % change | P-value | |
| N | 817 | 519 | −36 | 1788 | 1308 | −12 | 1308 | 1001 | −23 | |||
| Women | 250 (30.60) | 171 (32.95) | −32 | 0.368 | 617 (34.51) | 505 (32.21) | −18 | 0.159 | 449 (34.33) | 331 (33.07) | −26 | 0.526 |
| Men | 567 (69.40) | 348 (67.05) | −39 | 1171 (65.49) | 1063 (67.79) | −9 | 859 (65.67) | 670 (66.93) | −22 | |||
| Age | 0.638 | 0.352 | 0.001 | |||||||||
| <80 | 579 (70.87) | 374 (72.06) | −35 | 1288 (72.04) | 1152 (73.47) | −11 | 883 (67.51) | 738 (73.73) | −16 | |||
| ≥80 | 238 (29.13) | 145 (27.94) | −39 | 500 (27.96) | 416 (26.53) | −17 | 425 (32.49) | 263 (26.27) | −38 | |||
| Type of ACS | <0.001 | <0.001 | <0.001 | |||||||||
| Unstable angina | 143 (17.50) | 84 (16.18) | −41 | 272 (15.21) | 274 (17.47) | 1 | 167 (12.77) | 167 (16.68) | 0 | |||
| NSTEMI | 560 (68.54) | 325 (62.62) | −42 | 1249 (69.58) | 997 (63.58) | −20 | 944 (72.17) | 671 (67.03) | −29 | |||
| STEMI | 97 (11.87) | 57 (10.98) | −41 | 228 (12.75) | 95 (6.06) | −58 | 173 (13.23) | 63 (6.29) | −64 | |||
| Other MI | 8 (0.98) | 43 (8.29) | 438 | 14 (0.78) | 161 (10.27) | 1050 | 10 (0.76) | 75 (7.49) | 650 | |||
| Other ACS | 9 (1.10) | 10 (1.93) | 11 | 25 (1.4) | 41 (2.61) | 64 | 14 (1.07) | 25 (2.50) | 79 | |||
| AMG weight, mean (SD) | 32.92 (17.46) | 20.44 (16.29) | −38 | <0.001 | 31.82 (16.47) | 18.61 (14.44) | −41 | <0.001 | 31.19 (16.27) | 17.16 (13.85) | −45 | <0.001 |
| PCSA index, mean (SD) | 42.11 (15.27) | 42.68 (15.00) | 1 | 0.514 | 42.20 (14.62) | 41.24 (15.10) | −2 | 0.064 | 41.79 (14.56) | 42.05 (14.56) | 1 | 0.680 |
| Quantiles of PCSA index | 0.084 | 0.799 | 0.414 | |||||||||
| 1st | 202 (24.72) | 116 (22.35) | −43 | 422 (23.60) | 394 (25.13) | −7 | 324 (24.77) | 221 (22.08) | −32 | |||
| 2nd | 188 (23.01) | 113 (21.77) | −40 | 428 (23.94) | 376 (23.98) | −12 | 306 (23.39) | 262 (26.17) | −14 | |||
| 3rd | 187 (22.89) | 139 (26.78) | −26 | 432 (24.16) | 370 (23.60) | −14 | 305 (23.32) | 236 (23.58) | −23 | |||
| 4th | 215 (26.32) | 145 (27.94) | −33 | 472 (26.40) | 389 (24.80) | −18 | 335 (25.61) | 249 (24.88) | −26 | |||
| PCI during hospitalization | 353 (43.21) | 242 (46.63) | −31 | 0.220 | 826 (46.20) | 633 (40.37) | −23 | 0.001 | 619 (47.32) | 420 (41.96) | −32 | 0.010 |
| In−hospital mortality | 45 (5.51) | 46 (8.86) | 2 | 0.018 | 69 (3.86) | 73 (4.66) | 6 | 0.253 | 60 (4.59) | 48 (4.80) | −20 | 0.814 |
| Hospital length of stay (days), mean (SD); median (p25 to p75) | 9.41 (8.03); 7 (5 to 11) | 7.11 (6.34); 5 (3 to 9) | −24 | <0.001 | 8.88 (7.71); 7 (4 to 11) | 8.29 (7.21); 6 (4 to 10) | −7 | <0.001 | 9.47 (9.63); 7 (4 to 11) | 8.03 (6.97); 6 (4 to 10) | −15 | <0.001 |
Numbers indicate n (%) except if otherwise stated.