TABLE 1.
Strain no. | Hospital IDb | Age (yr) and sex of patientc | First treatment
|
Final treatment
|
||||
---|---|---|---|---|---|---|---|---|
Agentsd | Regimene | Clinical outcome | Agent(s) | Regimen | Clinical outcome | |||
SNG27 | Ue | 27, M | CDR | 100 mg × 3, p.o., 3 days | Failure | CRO | 1 g i.v., single dose | Cure |
SPX | 100 mg, 3 days | |||||||
SNG28 | Ya | 24, M | SPT | 2 g i.m., single dose | Cure | |||
DOX | 100 mg × 2, p.o., 7 days | |||||||
SNG32 | Ar | 19, F | CM | Suppository, 2 times | Not tested | |||
SNG33 | UO | 29, M | AZT | 1 g i.v., single dose | Failure | SPT | 2 g i.m., single dose | Cure |
SNG46 | Ya | 21, M | SPT | 2 g i.m., single dose | Cure | |||
DOX | 100 mg × 2, p.o., 7 days | |||||||
SNG50 | Ni | 19, M | CDR | 100 mg × 3, p.o., 3 days | Failure | SPT | 2 g i.m., single dose | NF |
SNG52 | An | 22, F | AMO | 375 mg × 4, p.o., 7 days | Failure | CDZ | 1 g i.v., single dose | Cure |
SNG53 | Kr | 24, M | CRO | 1 g i.v., single dose | Cure | |||
SNG54 | AY | 42, M | LVX | 100 mg × 3, p.o. | Failure | CDZ | 1 g i.v., single dose | Cure |
SNG57 | BM | 36, M | Unknown | |||||
SNG65 | Ni | 19, M | CDR | 100 mg × 3, 3 days | NFf | |||
SNG70 | BM | 33, M | Unknown | |||||
SNG74 | Ni | 30, M | SPT | 2 g i.m., single dose | Cure | |||
MIN | 100 mg × 2, 7 days | |||||||
SNG75 | Ni | 27, M | SPT | 2 g i.m., single dose | Cure | |||
MIN | 100 mg × 2, p.o., 7 days | |||||||
SNG76 | Ni | 29, M | CDZ | 1 g i.v., single dose | Cure | |||
SNG79 | Ni | 26, M | CDZ | 1 g i.v., single dose | Cure | |||
SNG81 | An | 19, M | CDZ | 1 g i.v., single dose | Cure |
Including isolates from clinical failure cases treated with CDR and AZT. Data for SNG27 and SNG33 have been previously reported (1).
Blind names of hospitals.
M, male; F, female.
CDR, cefdinir; DOX, doxycycline; MIN, minocycline; AMO, amoxicillin; SPX, sparfloxacin.
p.o., orally; i.m., intramuscularly; i.v., intravenously.
NF, not followed.