Fig. 2. JN-PK1 inhibited PI3K/Akt pathway through suppressing p-Akt^Thr308, p-Akt^Ser473 and p-mTOR^Ser2448. (A) OCI-My5 and HL-60 were treated with JN-PK1 at different concentrations from 0 to 20 μM for 24 h. (B) OCI-My5 and HL-60 were treated with JN-PK1 for different time from 0 to 24 h at the indicated concentration (20 μM).