Influence of quercetin on general parameters in experimental animalsa.
| Group | Glu (mmol L−1) | KW/BW (mg g−1) | BUN (mmol L−1) | Ccr (mL min−1 kg−1) | TG (mmol L−1) |
|---|---|---|---|---|---|
| NC | 5.74 ± 0.67 | 6.68 ± 0.58 | 10.06 ± 1.77 | 4.32 ± 1.05 | 0.32 ± 0.07 |
| DN | 33.05 ± 3.23* | 12.38 ± 1.34* | 23.82 ± 6.69* | 6.36 ± 1.00* | 0.90 ± 0.34* |
| DN + LQ | 26.53 ± 4.94*# | 10.40 ± 0.99*# | 15.51 ± 2.80# | 5.00 ± 0.36# | 0.50 ± 0.10# |
| DN + HQ | 16.83 ± 2.74*# | 9.96 ± 0.42*# | 14.53 ± 2.38# | 4.27 ± 1.11# | 0.56 ± 0.25# |
a
Values represented mean ± SD (n = 5 per group). NC, normal control; DN, diabetic nephropathy; LQ, low dose quercetin (50 mg kg−1 d−1); HQ, high dose quercetin (100 mg kg−1 d−1); Glu, glucose; BW, body weight; KW/BW, kidney-to-body weight ratio; Ccr, creatinine clearance rate; BUN, blood urea nitrogen. *P < 0.05 vs. NC, #P < 0.05 vs. DN.