Resistance index (RI) values of phospholipids with CA or 3-OMe–CA residues against a doxorubicin-resistant LoVo/DX cell line.
Compound | Acyl residue | RI | |
---|---|---|---|
sn-1 | sn-2 | ||
1a | — | — | — |
3a | CA | CA | 1.65 |
5a | PA | CA | 1.08 |
9a | CA | — | 2.13 |
10a | CA | PA | 1.05 |
1b | — | — | — |
3b | 3-OMe–CA | 3-OMe–CA | 0.15 |
5b | PA | 3-OMe–CA | 0.99 |
9b | 3-OMe–CA | — | 1.88 |
10b | 3-OMe–CA | PA | 1.2 |
DOX | — | — | 55.81 |