Skip to main content
. 2022 May 10;57(8):1250–1259. doi: 10.1038/s41409-022-01698-3

Fig. 4. FasL AM treatment of MPBCs increases their phagocytosis and reduces proinflammatory cytokine secretion by activated macrophages.

Fig. 4

100 ng/ml FasL AM treated and non-treated MPBCs were incubated with activated macrophages at different ratios. Percentage of high phagocytic (CFSE+high) macrophages per total CD11b+ population as well as secretion of TNFα, IL-6 and IL-8 were evaluated. Percentage of high phagocytic (CFSE+high) macrophages: (a) Representative flow cytometry dot plots, (b) results of the representative experiment are presented as mean ± SEM of technical duplicates, *P ≤ 0.05; ***P ≤ 0.001, Multiple unpaired T-test. c The effect of engulfment of apoptotic cells by activated macrophages on TNFα, IL-8 and IL-6 secretion. Results of a representative experiment are presented as Mean ± SEM of technical duplicates. Macrophages: cell ratio 1:5; *P ≤ 0.05; Multiple unpaired T-test.