Skip to main content
. 2022 May 9;22:523. doi: 10.1186/s12885-022-09632-y

Table 1.

The Gene Ontology (GO) function enrichment analysis of RUNX1 and neighbor genes in pan-cancer (Metascape database)

Category (GO) Term ID Description Count Log10(P)
Molecular Functions GO:0,008,134 transcription factor binding 25 -30.724
Molecular Functions GO:0,003,712 transcription coregulator activity 20 -22.598
Biological Processe GO:0,030,099 myeloid cell differentiation 16 -18.438
Cellular Components GO:0,005,667 transcription factor complex 15 -18.268
Biological Processes GO:0,016,570 histone modification 15 -15.205
Biological Processes GO:0,008,285 negative regulation of cell proliferation 16 -13.220
Biological Processes GO:0,002,521 leukocyte differentiation 14 -12.955
Biological Processes GO:0,045,596 negative regulation of cell differentiation 15 -12.086
Biological Processes GO:0,048,511 rhythmic process 10 -10.875
Molecular Functions GO:0,001,085 RNA polymerase II transcription factor binding 8 -10.545
Biological Processes GO:0,045,444 fat cell differentiation 9 -10.396
Biological Processes GO:0,071,407 cellular response to organic cyclic compound 11 -9.988
Biological Processes GO:0,018,394 peptidyl-lysine acetylation 8 -9.890
Biological Processes GO:0,048,732 gland development 10 -9.297
Biological Processes GO:0,051,098 regulation of binding 9 -8.692
Biological Processes GO:0,006,367 transcription initiation from RNA polymerase II promoter 7 -8.054
Biological Processes GO:0,045,786 negative regulation of cell cycle 10 -7.792
Biological Processes GO:0,016,055 Wnt signaling pathway 9 -7.395
Molecular Functions GO:0,035,035 histone acetyltransferase binding 4 -7.147
Biological Processes GO:0,031,400 negative regulation of protein modification process 10 -7.145