Table 5.
Univariate and multivariate analyses for the prognoses of pT1N1 gastric cancer patients
| Variables | 5-year OS rate | Univariate |
Multivariate |
||
|---|---|---|---|---|---|
| P | HR | 95% CI | P | ||
| Age (years) | 0.005* | ||||
| < 60 | 98.10% | ||||
| ≥ 60 | 81.80% | 6.491 | 0.805–52.325 | 0.079 | |
| Gender | 0.031* | ||||
| Male | 84.80% | 5.103 | 0.648–40.176 | 0.122 | |
| Female | 97.70% | ||||
| Tumor size (cm) | 0.168 | ||||
| ≤ 2 | 93.40% | ||||
| > 2 | 85.40% | ||||
| Tumor location | 0.027* | ||||
| Upper | 100% | ||||
| Middle | 77.40% | 3.761 | 1.086–13.033 | 0.037* | |
| Lower | 94.40% | ||||
| Gross type | 0.906 | ||||
| Ulcerated | 89.70% | ||||
| Non-ulcerated | 90.20% | ||||
| Degree of differentiation | 0.358 | ||||
| Differentiated | 84.20% | ||||
| Undifferentiated | 91.10% | ||||
| Histopathology | 0.486 | ||||
| Tub | 84.20% | ||||
| Por | 89.20% | ||||
| Sig | 100% | ||||
| Muc | 100% | ||||
| Examined lymph node | 0.644 | ||||
| Her-2 status | 0.015* | ||||
| Negative | 92.60% | ||||
| Positive | 73.30% | 4.517 | 1.303–15.657 | 0.017* | |
| Depth of tumor invasion | 0.308 | ||||
| T1a | 95.70% | ||||
| T1b | 88.40% | ||||
| Lymphovascular invasion | 0.682 | ||||
| Negative | 89.50% | ||||
| Positive | 92.90% | ||||
| Perineural invasion | 0.642 | ||||
| Negative | 89.70% | ||||
| Positive | 100% | ||||
| Treatment after surgery | 0.782 | ||||
| OBS | 89.10% | ||||
| ACT | 90.50% | ||||
*P < 0.05 was considered statistically significant. Tub, tubular adenocarcinoma; Por, poorly differentiated adenocarcinoma; Sig, signet-ring cell carcinoma; Muc, mucinous adenocarcinoma; T1a, mucosal invasion; T1b, submucosal invasion; OS, overall survival; HR, hazard ratio; CI, confidence interval; OBS, observation; ACT, adjuvant chemotherapy.