Figure 2.
Key regulation of m6A modification in tumor immunity. As shown, the m6A modification is involved in anti-tumor immunity and tumor immune evasion. m6A methylation plays an essential role in the maintenance of immune cell homeostasis and function. Moreover, m6A modification patterns have an indispensable role in overall TME infiltration and the immune evasive phenotype. The close correlation between m6A-related risk signatures and the tumor immune microenvironment landscape supports the prognostic value and therapeutic efficacy of m6A regulators in a variety of cancer types.