Table 3. Inhibition of SC2 Lentivector Entry^a.

	Ib	c (μM)c	VE (%)d	RV (%)e
1	4	10	46 ± 8	103
2	33	10	56 ± 12	107
3	11	50	4 ± 1	84
4	34	50	8 ± 6	76
5	35	50	25 ± 3	96f
6	45	50	31 ± 3	81
7	36	50	34 ± 3	97
8	3	50	36 ± 3	81
9	37	50	42 ± 32	97f
10	38	50	43 ± 26	37
11	39	50	52 ± 31	86f
12	40	50	64 ± 25	96f
13	46	50	65 ± 13	40f
14	47	50	83 ± 12	70
15	41	5	>100f	100
16	48	5	>100	94
17	49	5	>100	92
18	16	5	>100	89
19	42	10	97 ± 15	107
20	43	10	99 ± 12	87
21	44	10	103 ± 12	98

^aFrom normalized luminescence intensity of A549 human lung alveolar basal epithelium cells overexpressing ACE2 and TMPRSS2 after incubation with

^binhibitor candidates at

^cconcentrations c (1 h) and lentivirus with D614G SC2 spike protein (6 h), followed by 3 days for luciferase expression, reported as

^dvector entry (VE) in % (n = 3, ±SD).

^eRV: Relative cell viability. SD ≤ 10%.

^fSD > 10%.