Table 2.

Laboratory features and risk scores as predictors of early (28 day) vs. late mortality

	Early mortality		Late mortality
	OR (95% CI) a	P‐value	OR (95% CI) a	P‐value
Laboratory parameters
Haemoglobin (g/L)	0.994 (0.985–1.003)	0.210	0.972 (0.956–0.987)	<0.001
WBCs (× 109/L)	1.00 (0.98–1.02)	0.856	1.00 (0.98–1.03)	0.831
WBCs < 4 or WBCs > 12 (× 109/L)	2.06 (1.27–3.36)	0.003	1.22 (0.53–2.79)	0.643
Neutrophils (× 109/L)	1.15 (1.09–1.23)	<0.001	1.14 (1.03–1.25)	0.008
Eosinophils (× 109/L)	0.01 (0.00–1.10)	0.055	13.3 (0.66–267)	0.091
Lymphocytes (× 109/L)	0.97 (0.87–1.09)	0.622	0.99 (0.86–1.14)	0.853
Platelets (× 109/L)	1.00 (0.999–1.003)	0.649	1.002 (0.999–1.006)	0.166
Urea (mmol/L)	1.07 (1.04–1.11)	<0.001	1.03 (0.98–1.07)	0.228
Creatinine (μmol/L)	1.001 (1.00–1.003)	0.166	1.00 (0.998–1.003)	0.718
eGFR (mL/min/1.73 m2)	0.977 (0.968–0.985)	<0.001	0.986 (0.974–0.998)	0.027
ALP (IU/L)	1.003 (1.001–1.006)	0.011	1.007 (1.002–1.011)	0.003
Bilirubin (μmol/L)	1.003 (0.988–1.018)	0.689	1.023 (0.996–1.051)	0.095
CRP (mg/L)	1.004 (1.002–1.006)	<0.001	0.999 (0.995–1.003)	0.595
Albumin (g/L)	0.92 (0.88–0.96)	<0.001	0.90 (0.84–0.96)	0.001
Sodium (mmol/L)	1.07 (1.03–1.10)	<0.001	0.99 (0.93–1.05)	0.729
Potassium (mmol/L)	1.36 (0.96–1.93)	0.083	0.96 (0.54–1.71)	0.900
Risk scores
Clinical Frailty Scale	1.49 (1.33–1.66)	<0.001	2.04 (1.62–2.56)	<0.001
4C mortality score	1.34 (1.25–1.45)	<0.001	1.23 (1.12–1.36)	<0.001

ALP, alkaline phosphatase; CI, confidence interval; CRP, C‐reactive protein; eGFR, estimated glomerular filtration rate; OR, odds ratio; WBCs, white blood cells. Values in bold denote statistically significant results.

^a Odds ratios are derived from binary logistic regression with early or late mortality as the dependent variable, and per 1‐unit change in the variable depicted in each row as the independent variable.