Table 4.
Multivariable analysis of predictors for early (28 day) mortality
| OR (95% CI) a | P‐value | |
|---|---|---|
| (a) Clinical characteristics | ||
| Clinical Frailty Scale | 1.32 (1.13–1.55) | 0.001 |
| Age >65 years | 3.31 (1.48–7.42) | 0.004 |
| Shortness of breath | 1.46 (0.81–2.61) | 0.206 |
| Myalgia | 1.06 (0.46–2.45) | 0.883 |
| Confusion | 1.58 (0.88–2.86) | 0.127 |
| RR > 20 (breaths per minute) | 2.01 (1.19–3.40) | 0.009 |
| Hypoxia (SpO2 < 92%) | 1.65 (0.95–2.85) | 0.074 |
| Congestive heart failure | 2.13 (1.17–3.90) | 0.014 |
| Chronic kidney disease | 1.21 (0.71–2.06) | 0.481 |
| Hypertension | 1.76 (1.06–2.91) | 0.028 |
| Dementia | 1.02 (0.54–1.93) | 0.948 |
| (b) Laboratory parameters | ||
| Clinical Frailty Scale | 1.33 (1.16–1.53) | <0.001 |
| WBCs < 4 or WBCs > 12 (× 109/L) | 1.46 (0.77–2.79) | 0.246 |
| Neutrophils (× 109/L) | 1.07 (0.99–1.16) | 0.103 |
| Urea (mmol/L) | 1.00 (0.96–1.05) | 0.843 |
| eGFR (mL/min/1.73 m2) | 0.986 (0.973–0.999) | 0.031 |
| ALP (IU/L) | 1.002 (0.999–1.005) | 0.168 |
| CRP (mg/L) | 1.004 (1.001–1.007) | 0.007 |
| Albumin (g/L) | 0.98 (0.93–1.04) | 0.484 |
| Sodium (mmol/L) | 1.041 (0.998–1.085) | 0.060 |
ALP, alkaline phosphatase; CI, confidence interval; CRP, C‐reactive protein; eGFR, estimated glomerular filtration rate; OR, odds ratio; RR, respiratory rate; WBCs, white blood cells. Values in bold denote statistically significant results.
a
Odds ratios are derived from multivariable logistic regression with early mortality as the dependent variable, and CFS as well as (a) all clinical features, or (b) all laboratory parameters associated at univariable analysis with early mortality, as independent variables.