Table 2.
Comparison of muscle excitability data between healthy subjects and critically ill COVID‐19 patients
| COVID‐19 patients (N = 31) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Healthy subjects (N = 31) | Day 1 | P value | Day 2 | P value | Day 5 | P value | Day 10 | P value | |
| MRRP | 3.5 (±0.4) | 5.8 (±2.0) | <0.001 | 5.3 (±1.8) | <0.001 | 5.3 (±2.3) | <0.001 | 5.3 (±2.3) | <0.001 |
| ESN | 11.3 (±1.8) | 8.9 (±4.0) | 0.005 | 9.3 (±3.7) | 0.012 | 7.8 (±4.1) | <0.001 | 7.8 (±4.1) | <0.001 |
| LSN | 3.7 (±1.0) | 3.3 (±1.2) | 0.204 | 3.5 (±2.4) | 0.682 | 3.6 (±2.6) | 0.842 | 3.6 (±2.6) | 0.126 |
| XLSN | 2.5 (±0.6) | 2.2 (±1.1) | 0.288 | 2.1 (±1.3) | 0.115 | 2.2 (±1.1) | 0.180 | 2.2 (±1.1) | 0.087 |
| 5XLSN | 7.2 (±1.1) | 5.9 (±2.1) | 0.004 | 5.8 (±2.6) | 0.010 | 5.4 (±2.2) | <0.001 | 5.4 (±2.2) | 0.001 |
| Lat(15 Hz)Last | 85.3 (±2.6) | 88.6 (±5.1) | 0.002 | 87.6 (±5.7) | 0.050 | 89.0 (±8.2) | 0.027 | 89.1 (±6.2) | 0.003 |
| Lat(15 Hz)First | 94.9 (±1.8) | 96.6 (±2.8) | 0.004 | 97.2 (±2.7) | <0.001 | 96.7 (±6.4) | 0.164 | 97.6 (±3.2) | <0.001 |
| Lat(30 Hz)First | 96.3 (±2.2) | 100.4 (±4.4) | <0.001 | 100.3 (±4.7) | <0.001 | 100.3 (±8.1) | 0.015 | 100.7 (±6.1) | 0.001 |
Comparisons using independent samples t‐tests are presented as mean (±standard deviation). MRRP is given in ms; all other values are given in per cent.
5XLSN, extra late supernormality due to five conditioning stimuli; ESN, early supernormality; Lat(15 Hz)First, latency to the first response in train at 15 Hz; Lat(15 Hz)Last, latency to the last response in train at 15 Hz; Lat(30 Hz)First, latency to the first response in train at 30 Hz; LSN, late supernormality; MRRP, muscle relative refractory period; XLSN, extra late supernormality due to two conditioning stimuli.