Table 5.
Results of laboratory analysis
| CIM+ (N = 17) | CIM− (N = 14) | P value | |
|---|---|---|---|
| Day 1 | |||
| Bicarbonate (mmol/L) | 24.1 [20.5; 27.4] | 27.6 [25.0; 29.1] | 0.204 |
| pCO2 (mmHg) | 44.0 [42.0; 52.0] | 46.0 [41.5; 47.8] | 0.928 |
| pO2 (mmHg) | 62.0 [44.0; 78.0] | 76.0 [71.2; 81.0] | 0.986 |
| Base excess (mmol/L) | −0.7 [−4.0; 2.8] | 2.0 [0.3; 4.9] | 0.094 |
| Lactate (mmol/L) | 1.3 [1.2; 1.6] | 1.3 [1.0; 1.4] | 0.578 |
| Glucose (mmol/L) | 8.4 [7.7; 9.5] | 8.1 [7.6; 9.6] | 0.908 |
| Potassium (mmol/L) | 4.5 [4.3; 4.9] | 4.1 [3.8; 4.2] | 0.005 |
| Sodium (mmol/L) | 139.0 [136.0; 142.0] | 138.0 [135.2; 139.8] | 0.170 |
| Chloride (mmol/L) | 107.0 [105.0; 109.0] | 106.5 [101.2; 108.8] | 0.315 |
| pH | 7.4 [7.3; 7.4] | 7.4 [7.4; 7.4] | 0.040 |
| Creatinine (μmol/L) | 88.0 [66.0; 141.0] | 87.5 [75.0;97.5] | 0.205 |
| Creatine kinase (U/L) | 267.5 [92.5;1848.8] | 119.0 [53.0;293.0] | 0.153 |
| C‐reactive protein (mg/L) | 179.5 [114.8;234.0] | 160.0 [104.8;208.5] | 0.569 |
| Day 2 | |||
| Bicarbonate (mmol/L) | 25.5 [23.0;28.6] | 30.1 [27.6;31.5] | 0.087 |
| pCO2 (mmHg) | 42.0 [38.0;47.0] | 47.5 [45.2;50.0] | 0.025 |
| pO2 (mmHg) | 68.0 [64.0;74.0] | 55.5 [38.0;70.8] | 0.194 |
| Base excess (mmol/L) | 1.1 [−0.7;4.6] | 4.6 [2.6;6.4] | 0.132 |
| Lactate (mmol/L) | 1.6 [1.1;1.8] | 1.4 [1.0;1.7] | 0.172 |
| Glucose (mmol/L) | 8.8 [8.2;10.3] | 9.3 [8.3;10.2] | 0.900 |
| Potassium (mmol/L) | 4.2 [3.9;4.3] | 3.9 [3.6;4.1] | 0.031 |
| Sodium (mmol/L) | 140.0 [138.0;144.0] | 140.0 [138.0;142.0] | 0.794 |
| Chloride (mmol/L) | 108.0 [106.0;109.0] | 105.5 [101.5;109.8] | 0.285 |
| pH | 7.4 [7.4;7.4] | 7.4 [7.4;7.5] | 0.967 |
| Creatinine (μmol/L) | 110.0 [90.2;165.8] | 106.0 [92.0;123.0] | 0.219 |
| Creatine kinase (U/L) | 1672.5 [1372.2;2068.8] | 159.0 [159.0;159.0] | 0.293 |
| C‐reactive protein (mg/L) | 215.0 [133.5;311.0] | 171.0 [136.0;203.0] | 0.381 |
| Day 5 | |||
| Bicarbonate (mmol/L) | 29.2 [27.9;31.4] | 34.6 [31.6;36.4] | 0.002 |
| pCO2 (mmHg) | 45.0 [42.0;48.0] | 51.5 [48.5;55.5] | 0.007 |
| pO2 (mmHg) | 69.0 [64.0;74.0] | 61.5 [59.2;77.8] | 0.848 |
| Base excess (mmol/L) | 6.0 [3.6;6.7] | 9.1 [7.2;11.7] | 0.004 |
| Lactate (mmol/L) | 1.4 [1.1;1.8] | 1.4 [1.3;1.6] | 0.731 |
| Glucose (mmol/L) | 9.0 [8.2;10.3] | 8.3 [7.6;10.1] | 0.532 |
| Potassium (mmol/L) | 4.3 [4.0;4.6] | 4.0 [4.0;4.4] | 0.171 |
| Sodium (mmol/L) | 141.0 [138.0;145.0] | 142.0 [140.0;146.5] | 0.155 |
| Chloride (mmol/L) | 106.0 [104.0;109.0] | 105.5 [99.0;111.8] | 0.363 |
| pH | 7.4 [7.4;7.5] | 7.4 [7.4;7.5] | 0.625 |
| Creatinine (μmol/L) | 118.0 [97.0;169.5] | 88.0 [79.0;102.0] | 0.132 |
| Creatine kinase (U/L) | 154.5 [74.5;2823.2] | 543.0 [508.0;549.5] | 0.456 |
| C‐reactive protein (mg/L) | 136.0 [73.0;224.0] | 154.0 [63.2;252.0] | 0.973 |
| Day 10 | |||
| Bicarbonate (mmol/L) | 28.3 [24.8;32.0] | 32.5 [30.2;37.5] | 0.002 |
| pCO2 (mmHg) | 46.0 [40.0;53.0] | 45.5 [43.2;53.2] | 0.834 |
| pO2 (mmHg) | 68.0 [61.0;78.0] | 68.5 [65.2;78.0] | 0.123 |
| Base excess (mmol/L) | 3.4 [−1.0;6.1] | 8.9 [5.9;12.2] | 0.001 |
| Lactate (mmol/L) | 1.5 [1.3;1.7] | 1.5 [1.2;1.8] | 0.783 |
| Glucose (mmol/L) | 9.0 [8.0;9.8] | 8.7 [7.3;10.2] | 0.776 |
| Potassium (mmol/L) | 4.4 [4.2;4.7] | 4.0 [3.7;4.2] | 0.003 |
| Sodium (mmol/L) | 141.0 [138.0;144.0] | 142.5 [141.2;144.8] | 0.960 |
| Chloride (mmol/L) | 108.0 [103.0;110.0] | 106.0 [102.0;108.0] | 0.287 |
| pH | 7.4 [7.4;7.5] | 7.5 [7.4;7.5] | 0.005 |
| Creatinine (μmol/L) | 138.0 [113.0;204.0] | 81.5 [61.8;115.5] | 0.033 |
| Creatine kinase (U/L) | 443.0 [139.0;1419.8] | 222.0 [83.0;356.0] | 0.302 |
| C‐reactive protein (mg/L) | 68.0 [35.0;149.0] | 72.0 [36.8;94.5] | 0.350 |
CIM, critical illness myopathy.
All values are reported as median [interquartile range]. P values are unadjusted and refer to independent‐samples t‐tests.