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. 2021 Aug 28;8(11):ofab431. doi: 10.1093/ofid/ofab431

Table 1.

Minimum Inhibitory Concentration Values for Candida glabrata Isolates for Different Antifungal Agents With Clinical and Laboratory Standards Institute Interpretations

Drug Susceptibility (MIC, µg/mL) and Clinical Interpretation
Isolate 1 Isolate 2 Isolate 3 Isolate 4
MIC Int. MIC Int. MIC Int. MIC Int.
Caspofungin ≤0.25 S 0.25 I 0.5 R 0.5 I
Fluconazole 4 S 256 R >256 R 64 R
Voriconazole 0.25 NA 4 NA >8 NA
Anidulafungin 0.12 S 0.5 R 1 R
Rezafungin 2 NA
Micafungin 0.03 S 0.12 I 0.5 R
5-flucytosine ≤0.06 NA ≤0.06 NA
Posaconazole 1 NA >8 NA
Itraconazole 1 NA >16 NA
Amphotericin B ≤0.12 NA 1 NA 0.5 NA

Isolate 1: aortic graft explant in 2017; Isolate 2: thoracic duct embolization coil in 2019; Isolate 3: first aortic Dacron graft explant tissue isolate; Isolate 4: second aortic Dacron graft explant tissue isolate in 2020 (48-hour MIC data are reported due to insufficient growth at 24 hours; isolate possesses FKS2 D666Y mutation).

Abbreviations: I, intermediate; MIC, minimum inhibitory concentration; NA, not applicable; R, resistant; S, susceptible.