Table 1.
Demographics of Infant Participants
| All Infant Participants With Hemoglobin Measurements during NICU Hospitalization (N=97) | Infant Participants with Neonatal MRI Brain Imaging [at ~Term-Equivalence] (N=29) | Infant Participants with Bayley-III Cognitive Assessment at 12-months-old (N=34) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| Male (N=43) | Female (N=54) | All Infants (N=97) | p / M=F * | Male (N=19) | Female (N=10) | All Infants (N=29) | p / M=F * | Male (N=18) | Female (N=16) | All Infants (N=34) | p / M=F * | |
| Birth Weight (g) | ||||||||||||
| Mean (SD) | 725 (163) | 696 (174) | 709 (169) | p = 0.400 | 765 (153) | 798 (218) | 776 (175) | p = 0.673 | 734 (176) | 658 (192) | 698 (185) | p = 0.237 |
| Median [Min, Max] | 747 [279, 1010] | 687 [379, 997] | 712 [279, 1010] | 785 [394, 1010] | 896 [412, 988] | 801 [394, 1010] | 765 [394, 1010] | 633 [395, 984] | 694 [394, 1010] | |||
| Gestational Age (wks) | ||||||||||||
| Mean (SD) | 25.4 (1.61) | 25.3 (1.69) | 25.4 (1.65) | p = 0.629 | 25.5 (1.25) | 26.2 (1.06) | 25.8 (1.21) | p = 0.137 | 25.3 (1.54) | 24.8 (1.42) | 25.1 (1.49) | p = 0.296 |
| Median [Min, Max] | 25.7 [22.4, 28.4] | 25.5 [22.3, 28.4] | 25.7 [22.3, 28.4] | 25.9 [23.1, 28.6] | 26.1 [24.0, 28.1] | 26.0 [23.1, 28.6] | 25.8 [22.4, 27.4] | 25.0 [22.4, 26.9] | 25.4 [22.4, 27.4] | |||
| 12-Month Chronological Age (months) | ||||||||||||
| Mean (SD) | 16.3 (1.49) | 16.0 (0.758) | 16.1 (1.15) | p = 0.447 | 16.7 (2.03) | 15.9 (1.43) | 16.4 (1.83) | p = 0.377 | 15.8 (0.825) | 15.8 (0.476) | 15.8 (0.669) | p = 0.784 |
| Median [Min, Max] | 15.8 [14.4, 20.3] | 15.9 [14.9, 18.4] | 15.9 [14.4, 20.3] | 15.7 [14.4, 20.3] | 15.3 [14.9, 18.4] | 15.6 [14.4, 20.3] | 15.6 [14.4, 17.8] | 15.8 [15.0, 16.6] | 15.7 [14.4, 17.8] | |||
| 12-Month Corrected Age (months) | ||||||||||||
| Mean (SD) | 12.5 (1.36) | 12.3 (0.826) | 12.4 (1.10) | p = 0.508 | 13.0 (1.75) | 12.3 (1.48) | 12.8 (1.64) | p = 0.449 | 12.1 (0.877) | 12.0 (0.464) | 12.1 (0.697) | p = 0.864 |
| Median [Min, Max] | 12.0 [10.6, 15.8] | 12.1 [11.3, 14.9] | 12.1 [10.6, 15.8] | 12.2 [10.6, 15.8] | 11.7 [11.3, 14.9] | 12.1 [10.6, 15.8] | 11.9 [10.6, 14.3] | 12.1 [11.3, 13.0] | 11.9 [10.6, 14.3] | |||
| Intraventricular Hemorrhage (IVH), Germinal Matrix Hemorrhage (GMH), and Periventricular Leukomalacia (PVL) Grading | p = 0.890 | p = 0.161 | p = 0.492 | |||||||||
| Normal (No IVH/PVL) | 31 (72.1%) | 43 (79.6%) | 74 (76.3%) | 13 (68.4%) | 8 (80.0%) | 21 (72.4%) | 13 (72.2%) | 14 (87.5%) | 27 (79.4%) | |||
| Grade I IVH or GMH | 6 (14.0%) | 4 (7.4%) | 10 (10.3%) | 3 (15.8%) | 2 (20.0%) | 5 (17.2%) | 3 (16.7%) | 1 (6.2%) | 4 (11.8%) | |||
| Grade II IVH or GMH | 3 (7.0%) | 2 (3.7%) | 5 (5.2%) | 1 (5.3%) | 0 (0%) | 1 (3.4%) | 1 (5.6%) | 0 (0%) | 1 (2.9%) | |||
| Grade III IVH or GMH | 3 (7.0%) | 1 (1.9%) | 4 (4.1%) | 1 (5.3%) | 0 (0%) | 1 (3.4%) | 1 (5.6%) | 1 (6.2%) | 2 (5.9%) | |||
| Grade IV IVH or GMH -- periventricular hemorrhagic infarction | 0 (0%) | 3 (5.6%) | 3 (3.1%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| PVL Present | 0 (0%) | 1 (1.9%) | 1 (1.0%) | 1 (5.3%) | 0 (0%) | 1 (3.4%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
*
Independent Samples Student T-test for equal mean between males & females.