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. 2022 Apr 26;13:871769. doi: 10.3389/fimmu.2022.871769

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Copyright © 2022 Sun, Zhou, Guan, Liu, Yang, Wang, Gan, Zhou, Fan, Yi and Qiu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Landscape of infiltrating T cells in P-ICC and T-ICC. (A) t-SNE projections of subclustered T cells, labeled in different colors, and T cell origins from P-ICC or T-ICC. (B) Bar plots showing the proportion of T-cell subtypes in each sample. (C) Heatmap indicating the expression of selected gene sets in T subtypes, including naïve, inhibitory, effector/memory, proliferating, cytotoxic, and cell type. Pseudotime analysis of CD8⁺ (D) and CD4⁺ T cells (E) from P-ICC and T-ICC. T-cell subtypes and origins are labeled by colors.