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. 2022 Mar 11;11(9):1925–1936. doi: 10.1002/cam4.4533

TABLE 1.

Incidence and multiplicity of autochthonous intestinal tumor arising from Villincre; Smad4F / F ; Trp53F / F mice after CWP232291 treatment

Group CWP232291 treated Untreated
Total mice (n) 19 27
Dead mice before 20 weeks (n)

3

(adenoma, n = 2; unknown, n = 1)

4

(adenoma, n = 1; hyperplasia, n = 1; unknown, n = 2)

Remaining mice until 20 weeks (n) 16 23
Tumor‐bearing mice [n (%)] 9 (50.0)** 21 (84.0)
AdenoC. mice [n (%)] 6 (37.5)* 18 (78.3)
Tumor multiplicity 1.18 ± 0.36** 2.83 ± 0.39
Tumor diameter (mm) 4.25 ± 0.52 5.53 ± 0.97
*

p < 0.05.

**

p < 0.01.