TABLE 5.
Factors associated with the risk of CIN2+ in HIV‐infected women
| n | (%) | Logistic model | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariable | Multivariable with careHPV | Multivariable with HPV16 | |||||||||
| OR | (95% CI) | p | OR | (95% CI) | p | OR | (95% CI) | p | |||
| Age at baseline | |||||||||||
| 18–39 years | 399 | 30 | |||||||||
| 40–49 years | 151 | 13 | 1.16 | (0.6–2.2) | 0.67 | 1.45 | (0.7–2.9) | 0.28 | 1.41 | (0.7–2.8) | 0.33 |
| ≥50 years | 81 | 4 | 0.64 | (0.2–1.7) | 0.41 | 0.72 | (0.2–2.0) | 0.57 | 0.75 | (0.2–2.0) | 0.60 |
| CD4+ T lymphocytes count (seven missing) | |||||||||||
| ≥300 cells/mm3 | 403 | 27 | |||||||||
| <300 cells/mm3 | 221 | 20 | 1.39 | (0.7–2.5) | 0.29 | 1.11 | (0.55–2.2) | 0.75 | 1.70 | (0.9–3.3) | 0.11 |
| Nadir CD4+ T lymphocytes count (five missing) | |||||||||||
| ≥200 cells/mm3 | 254 | 24 | |||||||||
| <200 cells/mm3 | 372 | 23 | 0.63 | (0.4–1.2) | 0.13 | 0.57 | (0.3–1.14) | 0.11 | 0.51 | (0.3–0.9) | 0.04 |
| Positive CareHPV | |||||||||||
| No | 409 | 9 | |||||||||
| Yes | 222 | 38 | 9.18 | (4.5–20.6) | <0.0001 | 9.39 | (4.6–21.4) | <0.0001 | – | – | – |
| Cervical HPV‐16 | |||||||||||
| No | 574 | 35 | |||||||||
| Yes | 57 | 12 | 4.11 | (1.9–8.3) | 0.0001 | – | – | – | 4.26 | (1.9–8.7) | <0.0001 |
| Cervical HPV52 | |||||||||||
| No | 578 | 40 | |||||||||
| Yes | 53 | 7 | 2.05 | (0.8–4.6) | 0.10 | – | – | – | – | – | – |
Abbreviations: HIV, human immunodeficiency virus; HPV, human papillomavirus