Fig. 6. Validation of up and downregulated proteins by western blot analysis. Western blot analysis of Tap2, UBE1L (UBA7), CSF1R, IFI35, SP100, STAT1, and IFI44 in RAW macrophage cells was performed after 24 h treatment with 100 μM cGAMP and 100 μM c-di-GMP. β-actin was used as the control.