Effects of GE on blood biochemical parameters and bile flowa.
| Group | ALT (IU L−1) | AST (IU L−1) | ALP (IU L−1) | TBIL (μmol L−1) | DBIL (μmol L−1) | TBA (μmol L−1) | IL-1β (pg mL−1) | IL-6 (pg mL−1) | Bile flow (μg min−1 g−1 LW) |
|---|---|---|---|---|---|---|---|---|---|
| Vehicle | 6.3 ± 0.9 | 6.7 ± 2.0 | 8.1 ± 0.4 | 4.3 ± 0.5 | 9.4 ± 1.6 | 7.3 ± 1.5 | 52.9 ± 10.4 | 13.2 ± 5.1 | 0.94 ± 0.13 |
| GE | 7.8 ± 2.1 | 3.4 ± 0.7 | 11.1 ± 0.1 | 6.3 ± 2.7 | 6.1 ± 1.0 | 8.2 ± 3.6 | 48.4 ± 8.1 | 11.0 ± 4.0 | 1.07 ± 0.10 |
| ANIT | 87.5 ± 12.8b | 31.6 ± 3.6b | 154.6 ± 10.4b | 205.9 ± 17.1b | 31.6 ± 2.4c | 52.8 ± 6.0b | 133.1 ± 16.6b | 52.9 ± 8.2b | 0.52 ± 0.04c |
| GE + ANIT | 53.8 ± 4.0d | 21.6 ± 3.4d | 73.2 ± 1.7e | 146.5 ± 2.7d | 24.5 ± 1.5d | 38.2 ± 4.8d | 79.5 ± 7.7d | 26.4 ± 3.8d | 0.72 ± 0.05e |
a
Data are the mean ± S.E.M. (n = 8).
b
P < 0.01.
c
P < 0.001 vs. vehicle.
d
P < 0.05.
e
P < 0.01 vs. ANIT group.