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. Author manuscript; available in PMC: 2022 May 10.
Published in final edited form as: ACS Chem Biol. 2022 Feb 23;17(3):495–502. doi: 10.1021/acschembio.1c00954

Figure 2.

Figure 2.

Dynamics of the octamer core and histone H3 tails. (Top) The nucleosome core particle shown left with H2A/H2B dimers shown in dark blue and the H3/H4 tetramer shown in light blue, DNA is shown in gray. Octamer opening and DNA breathing are shown to the right. (Bottom) Models of the different conformational ensembles that the H3 tails adopt in the 147bp-nucleosome core particle (NCP), nucleosome with linker DNA, hexasome, and chromatasome. Coloring is the same as in top with the linker histone H1 shown in wheat.