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. 2022 May 10;17(5):e0268050. doi: 10.1371/journal.pone.0268050

Table 3. Disease outcomes by SARS-CoV-2 IgG antibody levels among the antibody cohort.

Low / High sCOVG ª Negative / Positive sCOVG ª
Index <10 N = 31 (%) Index >10 N = 40 (%) P Index <1 N = 15 (%) Index >1 N = 56 (%) P
COVID-19 worse severity: b
Severe 23 (74) 30 (75) 0.938 10 (67) 43 (77) 0.424
Critical 8 (26) 10 (25) 5 (33) 13 (23)
Maximal oxygen support needed: c      
Nasal cannula 18 (60) 23 (58) 0.888 8 (53) 33 (60) 0.554
Oxygen mask 4 (13) 8 (20) 2 (13) 10 (18)
Non-invasive 4 (13) 4 (10) 3 (20) 5 (9)
Intubation 4 (13) 5 (13) 2 (13) 7 (13)
Death 6 (19) 8 (20) 0.946 4 (27) 10 (18) 0.446
ICU admission 1 (3) 4 (10) 0.269 0 5 (9) 0.23
Hospital duration, d 9.1± 8.3 7.1 ±7.4 0.298 9.7± 9.0 7.5± 7.5 0.345

Abbreviations: sCOVG, SARS-CoV-2 IgG; COVID-19, coronavirus disease 2019; ICU, intensive care unit.

ª Antibody cohort included only admitted patients after the first two vaccine doses with levels taken earlier than 10 days before first positive PCR swab.

b Severity of illness was determined according to the National Institutes of Health and Israel Ministry of Health definitions.

c Oxygen mask include the need of a low flow mask (venturi mask) or a reservoir mask; Non-invasive include the need of continuous positive airway pressure (CPAP) or high-flow nasal cannula (HFNC).