Table 3. Disease outcomes by SARS-CoV-2 IgG antibody levels among the antibody cohort.
Low / High sCOVG ª | Negative / Positive sCOVG ª | |||||
---|---|---|---|---|---|---|
Index <10 N = 31 (%) | Index >10 N = 40 (%) | P | Index <1 N = 15 (%) | Index >1 N = 56 (%) | P | |
COVID-19 worse severity: b | ||||||
Severe | 23 (74) | 30 (75) | 0.938 | 10 (67) | 43 (77) | 0.424 |
Critical | 8 (26) | 10 (25) | 5 (33) | 13 (23) | ||
Maximal oxygen support needed: c | ||||||
Nasal cannula | 18 (60) | 23 (58) | 0.888 | 8 (53) | 33 (60) | 0.554 |
Oxygen mask | 4 (13) | 8 (20) | 2 (13) | 10 (18) | ||
Non-invasive | 4 (13) | 4 (10) | 3 (20) | 5 (9) | ||
Intubation | 4 (13) | 5 (13) | 2 (13) | 7 (13) | ||
Death | 6 (19) | 8 (20) | 0.946 | 4 (27) | 10 (18) | 0.446 |
ICU admission | 1 (3) | 4 (10) | 0.269 | 0 | 5 (9) | 0.23 |
Hospital duration, d | 9.1± 8.3 | 7.1 ±7.4 | 0.298 | 9.7± 9.0 | 7.5± 7.5 | 0.345 |
Abbreviations: sCOVG, SARS-CoV-2 IgG; COVID-19, coronavirus disease 2019; ICU, intensive care unit.
ª Antibody cohort included only admitted patients after the first two vaccine doses with levels taken earlier than 10 days before first positive PCR swab.
b Severity of illness was determined according to the National Institutes of Health and Israel Ministry of Health definitions.
c Oxygen mask include the need of a low flow mask (venturi mask) or a reservoir mask; Non-invasive include the need of continuous positive airway pressure (CPAP) or high-flow nasal cannula (HFNC).