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. 2022 May 9;7(9):e157915. doi: 10.1172/jci.insight.157915

Figure 2. Respiratory microbial diversity was reduced in nonresponders compared with responders.

Figure 2

(A) Respiratory microbial composition at the phylum level based on the relative abundance of operational taxonomic units (OTUs) for the BALF samples. P values were calculated using unpaired t test. *P < 0.05. (B and C) Alpha diversity analysis of the respiratory microbiome. (B) Rarefaction curve using the number of OTUs. (C) Bacterial alpha diversity based on Faith’s phylogenetic alpha diversity index. P values were calculated using the Kruskal-Wallis test. (D and E) Principal coordinate analysis of (D) the unweighted UniFrac distance matrices and (E) the weighted UniFrac distance matrices for the microbial communities. P values were calculated using the permutational multivariate ANOVA test. Responders (R; black), n = 6. Nonresponders (NR; red), n = 6.