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Schematic diagram of the mechanism by which miR-331-3p delivered by CAFs-derived EVs affect PC.
CAFs-derived EVs transfer miR-331-3p into PC cells where miR-331-3p inhibits SCARA5 expression to activate FAK pathway, enhancing the proliferation, migration, and invasion of PC cells in vitro and promoting the tumor growth in vivo, ultimately contributing to the progression of PC.
