Table 2.

Main pharmacokinetic parameters of rabbits after oral BCL (2.73 mg/kg) and intramuscular injection BCL-loaded PLGA microspheres (BCL 2.73 mg/kg).

Parameter	Group I	Group II
Tmax (h)	15.77 ± 6.77	36.00 ± 20.08
Cmax (ng/mL)	151.18 ± 55.00	30.64 ± 9.10
AUClast (h*ng/mL)	6054.29 ± 2626.12	6748.02 ± 2075.02
AUCINF-obs (h*ng/mL)	6276.17 ± 2626.66	7938.32 ± 1845.64
Vz/F-obs (mL/kg)	11570.36 ± 5251.75	81714.01 ± 73960.69
Cl/F-obs (mL/h/kg)	499.44 ± 164.52	396.84 ± 74.13
MRTlast (h)	28.70 ± 2.61	254.89 ± 48.58