Figure 2.
T22-PE24-H6 antitumor effect in a cell-derived subcutaneous SW1417 CRC model. (A) Antitumor effect of T22-PE24-H6 measured by the reduction of tumor volume (mm3). (B) Antitumor effect of T22-PE24-H6 measured by tumor weight (g) at the end of the experiment. (C) Increase in the number of cell death bodies in the SC SW1417 tumors counted in 10 high-power fields of H&E-stained tissue samples collected at the end of the experiment. (D) Follow-up of mouse body weight (g) during the repeated dose administration of 10 µg T22-PE24-H6 (three times a week, 8 total doses). All data are presented as mean ± s.e.m., N = 6. *p < 0.05; **p < 0.01.