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Protocols of treatment administration to different patients’ groups.
| Treatment | Group no. | Administration form | ITZ concentration |
|---|---|---|---|
| FC1 | 1 | Non-formulated ITZ cream | 0.1% |
| FC1′ | 2 | Non-formulated ITZ cream | 0.5% |
| FC2 | 3 | ITZ aspasomal cream | 0.1% |
| FC2′ | 4 | ITZ aspasomal cream | 0.5% |
| FC3 | 5 | Plain aspasomal cream | 0% |
| FC4 | 6 | Cream base | 0% |
