Table 4.

Clinical evaluation of napkin candidal dermatitis in 60 patients before and 10 days after the start of treatment.

Clinical assessment	Study formulae
	FC1	FC1′	FC2	FC2′	FC3	FC4	p Valuea
Area of rash (cm2)
Before	46 ± 9.5	46.2 ± 11.9	44.4 ± 10.2	47.1 ± 8.6	46 ± 12.9	42.3 ± 10.1	.931
After	18.2 ± 6.4	26.8 ± 6.2	17.1 ± 6.8	0 ± 0	43.2 ± 12.2	42.3 ± 10.1	<.001
p Valueb	<.001	<.001	<.001	<.001	.021	1
Redness
Before
None	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	.997
Mild	4 (40%)	3 (30%)	3 (30%)	2 (20%)	3 (30%)	3 (30%)
Marked	6 (60%)	7 (70%)	7 (70%)	8 (80%)	7 (70%)	7 (70%)
After
None	0 (0%)	0 (0%)	0 (0%)	10 (100%)	0 (0%)	0 (0%)	<.001
Mild	10 (100%)	10 (100%)	8 (80%)	0 (0%)	4 (40%)	3 (30%)
Marked	0 (0%)	0 (0%)	2 (20%)	0 (0%)	6 (60%)	7 (70%)
p Valueb	.014	.008	.025	.003	.317	1
Pustules
Before
0	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	.396
1–5	0 (0%)	2 (20%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)
5–20	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)
Innumerable	0 (0%)	1 (10%)	1 (10%)	0 (0%)	0 (0%)	0 (0%)
Confluent	5 (50%)	3 (30%)	4 (40%)	2 (20%)	5 (50%)	4 (40%)
Bullae/erosion	3 (30%)	4 (40%)	5 (50%)	8 (80%)	5 (50%)	6 (60%)
After
0	0 (0%)	2 (20%)	0 (0%)	10 (100%)	0 (0%)	0 (0%)	<.001
1–5	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)	0 (0%)
5–20	4 (40%)	3 (30%)	2 (20%)	0 (0%)	0 (0%)	0 (0%)
Innumerable	6 (60%)	4 (40%)	7 (70%)	0 (0%)	0 (0%)	0 (0%)
Confluent	0 (0%)	1 (10%)	1 (10%)	0 (0%)	4 (40%)	4 (40%)
Bullae/erosion	0 (0%)	0 (0%)	0 (0%)	0 (0%)	6 (60%)	6 (60%)
p Valueb	.007	.004	.004	.003	.317	1

Fisher’s exact test for qualitative data between groups. Wilcoxon’s signed rank test between before and after treatment in each group. Significant level at p value ≤.05.

^a One-way ANOVA test between the six groups followed by post hoc analysis between each two groups.

^b Paired samples t-test between before and after treatment in each group.