Biochemical characteristics of clinical specimensa.
| DN | MN | IgAN | MPGN | FSGS | |
|---|---|---|---|---|---|
| Number of subjects | 24 | 16 | 12 | 14 | 11 |
| Age (years) | 49.1 ± 9.7 | 58.6 ± 6.0 | 48.5 ± 4.0 | 54.7 ± 10.9 | 47.2 ± 7.8 |
| Duration of diabetes (months) | 144 (36–216) | 66 (1.2–156) | 66 (48–180) | 90 (12–300) | 48 (12–192) |
| Systolic blood pressure (mm Hg) | 148.3 ± 23.3 | 135.3 ± 22.3 | 140.0 ± 18.0 | 150.0 ± 24.6 | 153.0 ± 15.6 |
| Diastolic blood pressure (mm Hg) | 83.3 ± 15.4 | 82.0 ± 14.1 | 86.0 ± 10.9 | 89.3 ± 6.6 | 90.8 ± 12.6 |
| Creatinine (μmol L−1) | 116.0 ± 84.6 | 77.5 ± 23.6 | 93.1 ± 27.4 | 104.9 ± 46.0 | 97.8 ± 5 2.3 |
| Hemoglobin A1c (%) | 7.0 ± 1.2 | 6.4 ± 1.2 | 6.4 ± 1.0 | 7.2 ± 1.0 | 6.5 ± 0.4 |
| Hemoglobin (g L−1) | 118.6 ± 15.4 | 118.2 ± 24.9 | 130.7 ± 20.0 | 143.2 ± 13.3 | 127.5 ± 24.7 |
| Serum albumin (g L−1) | 35.7 ± 6.6 | 22.4 ± 7.8 | 37.1 ± 9.5 | 42.5 ± 4.9 | 37.6 ± 8.9 |
| Total cholesterol (mmol L−1) | 5.3 ± 1.5 | 7.3 ± 2.1 | 4.3 ± 0.8 | 4.8 ± 0.9 | 4.8 ± 1.2 |
| Triglyceride (mmol L−1) | 2.4 ± 1.1 | 2.5 ± 1.5 | 2.3 ± 1.2 | 1.7 ± 0.6 | 2.3 ± 0.8 |
| Urinary protein (g/24 h) | 2.6 (0.6–15.5) | 4.3 (1.3–5.7) | 0.8 (0.2–2.2) | 1.7 (0.2–8.4) | 2.7 (0.4–4.5) |
| Diabetic retinopathy | 16.6% | 16.0% | 20.0% | 14.3% | 9.0% |
| Hematuria | 16.6% | 50.0% | 70.0% | 7.1% | 27.3% |
a
All values are presented as mean ± SD. DN: diabetic nephropathy; MN: membranous nephropathy; IgAN: IgA nephropathy; MPGN: mesangial proliferative glomerular nephritis; FSGS: focal segmental glomerular sclerosis.