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. 2022 May 10;12:7665. doi: 10.1038/s41598-022-11860-y

Table 2.

Clinical characteristics of patients with CD and matched controls.

CD patients
N = 278*
Controls
N = 1112
p value
Sex (n, %)
Male 195 (70.1%) 780 (70.1%)
Female 83 (29.9%) 332 (29.9%)
Age at diagnosis, year (median, range) 27 (12, 63) N/A
Follow-up, month (median, range) 92.5 (0, 465) N/A
Comorbidities (n, %)
Hypertension 22 (7.9%) 88 (7.9%)
Diabetes mellitus 7 (2.5%) 28 (2.5%)
Dyslipidemia 7 (2.5%) 28 (2.5%)
Viral hepatitis 32 (11.5%) N/A
Coronary artery disease 7 (2.5%) N/A
Chronic kidney disease 9 (3.2%) N/A
Location at diagnosis (n, %)
Terminal ileal (L1) 41 (16.7%) N/A
Colonic (L2) 116 (47.4%) N/A
Ileocolonic (L3) 88 (35.9%) N/A
Behavior at diagnosis (n, %)
Non-stricturing & non-penetrating (B1) 160 (65.0%) N/A
Stricturing (B2) 65 (26.4%) N/A
Penetrating (B3) 21 (8.5%) N/A
SES-CD (Median, SD) 7 (5) N/A
Smoking (n, %) 0.60
Never 223 (80.2%) 866 (77.9%)
Past 15 (5.4%) 77 (6.9%)
Current 40 (14.4%) 169 (15.2%)

*Inclusion criteria: patients aged 12–64 years with complete information on hypertension, diabetes, hyperlipidemia, and smoking status.