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. 2022 Feb 5;126(10):1401–1409. doi: 10.1038/s41416-022-01711-y

Fig. 2. Recurrence-free survival for TNBC patients by BRCA1-like status and allocated adjuvant treatment.

Fig. 2

Kaplan–Meier curves of RFS for TNBC patients with BRCA1-like (a) and non-BRCA1-like tumours (b) according to treatment. Number of events and patients at risk are reported below the figure. Unadjusted hazard ratios are derived from Cox regression models (a, b). Similar results were obtained when HRs were adjusted for clinicopathologic variables. c Forest plot of hazard ratios for recurrence-free survival according to BRCA1-like status and treatment. Patients had been randomly assigned between adjuvant TX + CEX or T + CEF. HR hazard ratio, CI confidence interval, RFS recurrence-free survival, TNBC triple-negative breast cancer, TX + CEX 3 cycles of capecitabine plus docetaxel 3-weekly, followed by 3 cycles of cyclophosphamide, epirubicin and capecitabine, 3-weekly, T + CEF 3 cycles of docetaxel 3-weekly, followed by 3 cycles of cyclophosphamide, epirubicin and fluorouracil, 3-weekly.