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. 2022 Mar 21;126(10):1470–1480. doi: 10.1038/s41416-022-01763-0

Table 1.

Overall response rates (ORR) and histologic subtypes in Phase II trials of anti-PD-1/PD-L1 therapy in ovarian cancer.

Trial Monotherapy ORR Literature
UMIN00000571 Nivolumab

1/2 clear cell (50%)

2/18 others (11%)

Hamanishi et al., 2015 [48]
NCT01375842 Atezolizumab

1/1 clear cell (100%)

1/9 others (11%)

Liu et al., 2019 [49]
NCT02674061 (KEYNOTE-100) Pembrolizumab

3/19 clear cell (16%)

24/332 others (7.2%)

Matulonis et al., 2019 [50]

Matulonis et al., 2020 [51]

NCT01772004 (JAVELIN Solid Tumour) Avelumab

2/2 clear cell (100%)

10/123 others (8.1%)

Disis et al., 2019 [52]