Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 10;13:2314. doi: 10.1038/s41467-022-29614-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a The phylogenetic pattern for HA and NA inferred using a standard host-specific local clock (HSLC) model. b A monophyletic cluster for human pandemic and seasonal viruses estimated for HA and NA using an extended HSLC model (and using either model for all other segments). The star denotes the branch that is allowed to have a separate evolutionary rate in the HSLCext model. c Evolutionary rate estimates for the human lineage (first box) and the seasonal ancestral branch (second box) under the extended HSLC model for each segment ordered according to difference in these two rates. The boxes are colored according to the dN/dS estimate for the human lineage and the seasonal ancestral branch in each segment. The horizontal line in the whisker plots represents the mean. The lower and upper bounds of the boxes indicate the first and third quartile, respectively. Vertical lines are the upper and lower whisker representing the minimum of the largest value and 1.5 times the inter quartile distance, respectively the maximum of the smallest value and 1.5 times the inter quartile distance. Sample size from the MCMC chain is 2702 for NA and 4502 for all other segments. Source data are provided as a Source Data file.