Table 2 –
Summary of treatment-related toxicities
| AE terminology | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Total | |
|---|---|---|---|---|---|---|---|
| 1 | Abdominal pain | 1 | 1 | 2 | |||
| 2 | Alkaline phosphatase increased | 2 | 2 | ||||
| 3 | ALT increased | 1 | 1 | ||||
| 4 | AST increased | 1 | 1 | ||||
| 5 | Epigastric pain | 1 | 1 | ||||
| 6 | Fatigue | 1 | 1 | 2 | |||
| 7 | Lymphocyte count decreased | 1 | 1 | ||||
| 8 | Nausea | 2 | 1 | 3 | |||
| 9 | Small intestinal perforation | 1 | 1 | ||||
| 10 | Vomiting | 1 | 1 | ||||
| Total: grade 1 | 11 | ||||||
| Total: grade 2 | 3 | ||||||
| Total: grade 3 | 1 | ||||||
| Total: grade:4 | 0 | ||||||
| Total: grade:5 | 0 | ||||||
| Sum of grades | 15 |
AE = adverse event; ALT = alanine aminotransferase; AST = aspartate transaminase.