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. 2022 Apr;11(4):897–907. doi: 10.21037/tcr-21-1920

Table 3. Different expert guidelines recommend the use of multigenic assays.

Multigenetic assay ASCO NCCN St. Gallen EGTM
Oncotype Dx pN0 pN0; pN1 (1–3 positive nodes) pN0; pN1 (1–3 positive nodes) pN0; pN1 (1–3 positive nodes)
Mammaprint Not determined Not determined pN0; pN1 (1–3 positive nodes) pN0; pN1 (1–3 positive nodes)
Endopredict pN0 Not determined pN0; pN1 (1–3 positive nodes) pN0; pN1 (1–3 positive nodes)
PAM50 pN0 Not determined pN0; pN1 (1–3 positive nodes) pN0; pN1 (1–3 positive nodes)
BCI pN0 Not determined pN0; pN1 (1–3 positive nodes) pN0

ASCO, American Society of Clinical Oncology; NCCN, National Comprehensive Cancer Network; EGTM, European Organization Tumor markers; PAM50, mRNA expression of 50 genes; BCI, breast cancer index.