Table 3. Different expert guidelines recommend the use of multigenic assays.
Multigenetic assay | ASCO | NCCN | St. Gallen | EGTM |
---|---|---|---|---|
Oncotype Dx | pN0 | pN0; pN1 (1–3 positive nodes) | pN0; pN1 (1–3 positive nodes) | pN0; pN1 (1–3 positive nodes) |
Mammaprint | Not determined | Not determined | pN0; pN1 (1–3 positive nodes) | pN0; pN1 (1–3 positive nodes) |
Endopredict | pN0 | Not determined | pN0; pN1 (1–3 positive nodes) | pN0; pN1 (1–3 positive nodes) |
PAM50 | pN0 | Not determined | pN0; pN1 (1–3 positive nodes) | pN0; pN1 (1–3 positive nodes) |
BCI | pN0 | Not determined | pN0; pN1 (1–3 positive nodes) | pN0 |
ASCO, American Society of Clinical Oncology; NCCN, National Comprehensive Cancer Network; EGTM, European Organization Tumor markers; PAM50, mRNA expression of 50 genes; BCI, breast cancer index.