Table 1. Case reports in which GCP either co-occurred with or resembled gastric neoplasms.
Ref. | Age | Sex | Prior gastric surgery | Symptom | Involved gastric layer(s) | Gastric tumor | GCP IHC | Treatment | Survival outcome |
---|---|---|---|---|---|---|---|---|---|
(9) | 63 | M | No | Abdominal pain | Mucosa | ADC | KCNE2, ER | Distal gastrectomy | NR |
(10) | 55 | M | No | No stomach or intestinal symptoms | Submucosa | ADC | NR | Endoscopic submucosal dissection | AWED, 39 months |
(11) | 45 | M | No | Epigastric abdominal pain and black stool | Mucosa, submucosa | ADC | NR | Total gastrectomy with esophagojejunostomy, abdominal lymphadenectomy, feeding jejunostomy, and bilateral vagotomies | NR |
(12) | 51 | M | No | Abdominal pain | Submucosa, muscularis propria, subserosa | ADC | Ki-67, p53, p21WAF1/CIP1 | Total gastrectomy | AWED, 10 years |
(13) | 83 | F | Gastrojejunostomy 50 years prior | Epigastric discomfort | Mucosa, submucosa | ADC, signet ring cell carcinoma | Ki-67 | Distal gastrectomy, regional lymphadenectomy | AWED, 46 months |
(14) | 67 | M | No | Melena, ulcerated bleeding | Submucosa, muscularis propria | No tumor observed. GCP lesion mimicked GIST in GI tract bleeding and endoscopic ultrasonography | NR | Surgical resection of the lesion | NR |
(15) | 61 | M | No | None | Mucosa, submucosa, muscularis propria | No tumor observed. GCP lesion mimicked solid submucosal tumors in radiologic evaluation | CD68 | Laparoscopic wedge resection | AWED. Duration not reported |
GCP, gastritis cystica profunda; IHC, immunohistochemistry; ADC, adenocarcinoma; NR, not reported; AWED, alive with no evidence of disease; GIST, gastrointestinal stromal tumor; GI, gastrointestinal.