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. 2022 Apr 27;28:1610315. doi: 10.3389/pore.2022.1610315

TABLE 1.

Clinicopathological characteristics and preoperative laboratory parameters of patients with colon cancer liver-only metastases.

Parameters N (%) Median (range) Cut-off value RFS/OS
Age (yrs) 65 (38–80) 62/66
<62 23 (34)
≥62 44 (66)
<66 35 (52)
≥66 32 (48)
Gender
male 36 (54)
female 31 (46)
Type of surgery used for metastasectomy
laparoscopy 11 (16)
open 56 (84)
Resection margin
R0 46 (69)
R1 21 (31)
Synchronicity of primary surgery and metastasectomy
synchronous 7 (10)
metachronous 60 (90)
Preoperative (metastasectomy) chemotherapy ± targeted therapy
none 16 (24)
yes 51 (76)
targeted 43 (84)
Postoperative (metastasectomy) chemotherapy ± targeted therapy
none 18 (27)
yes 49 (73)
targeted 27 (55)
Pre- or postoperative chemotherapy ± targeted therapy
none 3 (4)
yes 64 (96)
targeted 48 (75)
WBC (G/l) 6.8 (3.5–12.5) 6.8/7.1
<6.8 32 (48)
≥6.8 35 (52)
<7.1 35 (52)
≥7.1 32 (48)
neutrophil (G/l) 4.3 (1.2–9.2) 4/4.8
<4 27 (40)
≥4 40 (60)
<4.8 41 (61)
≥4.8 26 (39)
lymphocyte (G/l) 2 (0.8–3.7) 1.94/2
<1.94 32 (48)
≥1.94 35 (52)
<2 36 (54)
≥2 31 (46)
platelet (G/l) 244 (105–446) 210/184
<210 20 (30)
≥210 47 (70)
<184 10 (15)
≥184 57 (85)
NLR 2 (0.7–8.8) 2/1.7
<2 30 (45)
≥2 37 (55)
<1.7 18 (27)
>1.7 49 (73)
SII (G/l) 502 (125–1952) 535/290
<535 39 (58)
≥535 28 (42)
<290 9 (16)
≥290 58 (84)
GOT (U/l) 25 (13–343) 24/24
<24 22 (37)
≥24 37 (63)
NA 8
GPT (U/l) 22 (9–296) 31/17
<31 48 (80)
≥31 12 (20)
<17 14 (23)
≥17 46 (77)
NA 7
Site of progression
liver 33 (63)
lung 5 (10)
liver+lung 7 (13)
other 7 (13)
Extent of progression
single 41 (61)
multiple 11 (16)
none 15 (22)